Cortical Labs launches the CL1, the world’s first commercial biological computer powered by human brain cells. Discover how Synthetic Biological Intelligence is redefining AI, biotech, and computing.
In a groundbreaking fusion of biotechnology and artificial intelligence, Australian startup Cortical Labs has launched the CL1, the world’s first commercial biological computer powered by living human brain cells. Debuted at MWC 2025 in Barcelona, the CL1 marks a new frontier in computing through what the company describes as “Synthetic Biological Intelligence” (SBI)—an innovative blend of human neurons and silicon technology.
A Living Computer: How the CL1 Works
At the heart of the CL1 is a revolutionary system that integrates lab-grown neurons derived from human stem cells with a silicon chip. These neurons thrive in a nutrient-rich medium and form dynamic neural networks capable of electrical communication. Through Cortical Labs’ proprietary operating system (biOS), these networks interact with a simulated digital environment and can be programmed in real-time.
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To support this delicate biological interface, the CL1 includes a built-in life support system that manages temperature, gas levels, nutrient flow, and waste filtration—keeping the neurons alive and functioning optimally for up to six months. This biological infrastructure also operates with remarkable energy efficiency, consuming significantly less power than conventional supercomputers.
Redefining AI: The Biological Advantage
Unlike traditional AI, which mimics brain processes through digital algorithms, the CL1 uses actual living neurons, offering unparalleled adaptability, learning speed, and efficiency. These cells, refined over billions of years of evolution, enable the system to outperform even the most sophisticated AI models in certain types of tasks—potentially including pattern recognition, problem-solving, and autonomous adaptation.
Furthermore, the CL1 offers a more ethical and human-relevant alternative to animal testing, especially valuable for research in drug development, neurological disease modeling, and advanced robotics. The platform is highly modular, equipped with USB ports and expansion capabilities, allowing seamless integration with sensors, cameras, and robotic actuators.
Market Rollout and Remote Access
Cortical Labs intends to make the CL1 available to research institutions and labs starting in the second half of 2025, with each unit priced at approximately $35,000. To extend access globally, the company is also launching the Cortical Cloud, a Wetware-as-a-Service (WaaS) platform. This cloud-based system will enable scientists and developers to remotely interface with living neural networks, expanding the reach of SBI technology worldwide.
The project has attracted $11 million in funding from major investors, including Horizons Ventures, Blackbird Ventures, LifeX Ventures, Radar Ventures, and In-Q-Tel, reflecting growing enthusiasm for the convergence of biology and computing.
The Future of Intelligence
The introduction of the CL1 signals a pivotal shift in how we approach computing and intelligence. By merging neuroscience with AI, Cortical Labs is not only pushing the boundaries of technology but also providing researchers with a powerful new tool to decode the mysteries of the brain and develop next-generation applications in healthcare, robotics, and cognitive science.
As the first commercially available biological computer, the CL1 could become a cornerstone in the evolution of artificial intelligence—where living systems and machines learn and grow together.